Take-out Tuesday, Butternut Squash, Spinach & Pepperoni Lasagna

Please join me in praying

for all my friends and neighbors on the Gulf Coast

who are being impacted by Hurricane Sally…

And everyone on the West Coast

being impacted by the horrible fires…

I was too stressed out and worried to cook yesterday

so I am re-sharing this recipe which I hope you enjoy

This is a short cut lasagna

Perfect for a cozy weeknight supper


Fresh or frozen cubed butternut squash, fresh spinach,

no boil lasagna sheets, grated Parmesan cheese

Make this a great vegetarian meal

or you can add pepperoni slices


A 5 minute Parmesan Cream Sauce binds everything happily together

Or use a prepared Alfredo sauce to make assembly even easier

Place squash on a lined sheet pan,

Season with salt, pepper, garlic, olive oil, and ginger*

Roast at 400 degrees for 20 minutes

*The ginger helps balance the sweetness of the squash


Layer pepperoni between paper towels on a plate

Microwave for 20 seconds to render fat


Once squash is done, assembly takes only minutes

Begin assembly with a layer of sauce,

then pasta sheets, squash, spinach,

riotta, and pepperoni,

repeating layers again and ending with pasta sheets on top

Cover the pasta sheets with sauce, Parmesan and pepperoni


Cover and refrigerate at this point for up to 24 hours before baking


Butternut Squash, Spinach & Pepperoni Lasagna

This is a unique version of a vegetable lasagna, and you can keep it vegetarian or add pepperoni for an extra flavor
Prep Time 25 minutes
Cook Time 45 minutes
Course Main Course
Cuisine American
Servings 4


  • 6 no boil lasagna sheets
  • 1 lb butternut squash cubes, fresh or frozen
  • 1 tsp minced garlic
  • 1/4 tsp ginger
  • olive oil
  • salt & pepper
  • 24-30 pepperoni slices, optional
  • 1/2 bag fresh spinach leaves, 4-6 cups
  • 1 cup ricotta cheese
  • 2 oz grated Parmigiano Reggiano cheese
  • 1 1/4 cups Parmesan Cream Sauce or Alfredo Sauce


  • Place squash on parchment paper lined baking sheet and sprinkle with minced garlic. Drizzle with olive oil and season with salt and pepper. Toss squash cubes to coat and distribute seasonings. Bake at 400 degrees for 20 minutes.
  • Lay pepperoni slices on a paper towel lined plate and top with another paper towel. Microwave on high for 20 seconds to render the fat.
  • Spread about 1/4 sauce into the bottom of small greased baking dish. Top with 2 lasagna sheets, end to end for a rectangular dish or side by side for a square dish.
  • When squash is done place 1/2 on top of lasagna sheets in dish. Next layer on 1/2 the spinach leaves. Top with 1/2 ricotta, in small dollops. Season ricotta with a little salt and pepper. Top with 1/3 of pepperoni slices and drizzle with a little Parmesan Cream Sauce. Repeat layers. Top with remaining 2 sheets of lasagna and spread with remaining sauce, sprinkle with Parmigiano Reggiano and top with remaining 1/3 of pepperoni. Cover and refrigerate up to 24 hours if desired.
  • Bake uncovered 30-60 minutes, or until hot and bubbly. Baking time will be longer for refrigerated lasagna than lasagna baked right after assembly. Let sit for 10 minutes to set.
Keyword Alfredo sauce, butternut squash, easy dinner, fresh spinach, lasagna, Parmesan cream sauce, pepperoni, vegetable lasagna

Parmesan Cream Sauce

this homemade Alfredo type sauce takes only minutes to make
Prep Time 5 minutes
Cook Time 5 minutes
Course condiment
Cuisine American


  • 3/4 cup half and half
  • 1/4 cup white wine or water
  • 2 T all purpose flour
  • 2 T unsalted butter
  • 1 oz. Parmigiano Reggiano


  • melt butter in small sauce pan over medium heat. Add flour and stir until incorporated. Add liquids and stir.
  • Cook several minutes until thickened about 4-5 minutes. Add 1 oz. Parmigiano Reggiano and stir into sauce.


This makes about 1 1/4 cup sauce, double the recipe as needed
Keyword Alfredo sauce, Parmesan cream sauce, white sauce

Let sit for 10 minutes to set before cutting and serving


The aroma while baking is enticing 


It’s a little sweet, a little spicy, and creamy dreamy good!

Wonderful Fall Comfort Food!

I will be joining these fabulous parties and blogs:

Meal Plan Monday   Love Your Creativity  Over the Moon

Between Naps on the Porch,  Celebrate Your Story,

All About Home/ Common Ground Follow the Yellow Brick Home

Make it Pretty Monday Tasty Tuesday   Oh My Heartsie Girl

Turn About Tuesday  Full Plate Thursday  Centerpiece Wednesday

Thursday Favorite Things  Creatively Crafty   Creative Cumpulsions

29 Responses to “Take-out Tuesday, Butternut Squash, Spinach & Pepperoni Lasagna”
  1. Sounds like comfort food Jenna! Please stay safe:@)

  2. Mary says:

    Looks delish Jenna! Keeping everyone in the path Sally and those impacted by the fires and smoke in our thoughts and prayers. Hope your beach house is battened down and stays safe ❀️

  3. Jenna, I am praying for all those in the path of Sally and all those impacted by the tragic fires. I hope your beautiful beach house will be safe. You are in my prayers πŸ™πŸ»β™₯️

  4. susan says:

    Our prayers are with you and everyone in the beautiful Gulf Coast. πŸ™. I know it will be a long few days for you waiting for Sally to pass. Hoping damage will not be extensive.

  5. Nancy says:

    Looks delicious!
    But praying for everyone in the path of Sally. Hoping your place will not be impacted! πŸ™πŸ»πŸ™πŸ»πŸ™πŸ» Praying for you dear friend.
    Prayers for all those fires to cease… now! πŸ™πŸ»πŸ™πŸ»πŸ™πŸ»

  6. Shannon@Belle Bleu Interiors says:

    Good morning, Jenna! This looks like the perfect autumn comfort food! It sounds delicious and a wonderful dish to enjoy on a cool fall day. Happy Tuesday! Take care!

  7. Rosie M. says:

    Oh, Jenna, my thoughts and prayers are with you. Our air quality is the pits right now. My daughter in Monrovia had to evacuate because the air in her house was so bad! We wake up to an orange sun every day. As soon as I saw the path of Sally, I started worrying about you. Mother Nature is surely making a statement right now. Please take care.

    • Thank you sweet Rosie, I pray for you and yours too, I have a ton of family in California, and it sounds so awful! I grew up in So Cal and remember the terror of fire evacuations, scary stuff…and now I get to deal with hurricanes πŸ™‚

  8. Jenna I seriously didn’t know what to fix for dinner tonight, but since I have seen your recipe post I know just what to fix. My boss brought me in some squash that I hadn’t fixed yet. This looks so yummy. Thanks for sharing!

  9. Sarah Anderson says:

    Jenna, this looks so tasty!!!

  10. Bonnie Morgan says:

    Jenna, Praying for the Gulf Coast. Keeping your house in our prayers.
    Praying for the west affected by the fires too. Wish we could send rain from the Gulf out there.
    Your recipe looks so good. I would love it. Thanks for the steps.

    • Thanks so much Bonnie! I have a lot of family in Calif and so far they are all good except the air quality is so bad they all have scratchy throats…Oh how I wish we could send them our rain!

  11. thefrenchhutch says:

    Jenna, I am thinking about you and your family and friends knowing Sally is causing so much damage. Know you are in thoughts and prayers, and for no damage to your beach home…….
    The recipe sounds delicious.

  12. Cyndi Raines says:

    This does look yummy! You think of the neatest dishes! Yes, praying for our nation, the fires, the hurricanes, the riots, etc. Prayers for you Jenna and your family and the extended family in California. β™₯οΈπŸ›

  13. Shelia says:

    I will keep the coast in my prayers for sure. Sally is moving so slow, and that seems to be making things worse with the rain that is hovering and drenching areas. Here is Georgia today (Wed.) is a really overcast and blustery day, with a fine mist, So Sally is moving our way too. Praying that all areas escape loss of lives and homes. Love to you and your family–your friends are out here keeping you and yours in our hearts.

  14. rawsonjl says:

    That sounds absolutely delicious!! I love just about anything with butternut squash and spinach. Pinned.

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